Postdoctoral Researcher in Pharmacometrics
University of Oxford
We are seeking to appoint a Postdoctoral Researcher in Pharmacometrics to conduct quantitative pharmacology research with the aim to improve and optimise current and newly developed treatments for malaria and other neglected tropical diseases. This will be done by developing mathematical and statistical models, to describe the time course of drug concentrations and effect. You will work closely with scientists, software engineers, data managers, and collaborators across the Mahidol Oxford Tropical Medicine Research Unit, and the wider Tropical Network Programme. Wet lab work will not be involved in this role.
MORU is a well-established and highly productive research collaboration between the Faculty of Tropical Medicine, Mahidol University, the University of Oxford, and the Wellcome Trust (UK). The unit has been conducting research here for 40 years and is recognised as a world leader in tropical medicine research. Our main research interests are the pharmacology, epidemiology, diagnosis, pathophysiology and treatment of infectious diseases, which cause illness and deaths throughout this region.
The Department of Clinical Pharmacology is a part of MORU and focuses on quantifying medicine in patient samples from clinical trials, proteomic/metabolomic/lipidomic research, pharmacometric data analysis, and medicine quality research. The department is today one of the world’s leading laboratories for pharmacological research on antimalarial drugs and we comprise a diverse team of approximately 25 persons.
You will be responsible for developing physiologically-based pharmacokinetic (PBPK) models using clinical and preclinical data from MORU and collaborators in order to optimise treatments in infectious disease contexts. You will take part in experimental design, PBPK model development and verification, and translation of model outputs to inform clinical decision-making. You will also provide technical mentorship and practical guidance to junior members of the research group. You will manage your own academic research and administrative tasks and you will adapt existing and develop new research methodologies and materials.
It is essential that you hold a PhD/DPhil (or close to completion) in pharmacokinetics, pharmaceutical sciences, physiology, mathematics, or a related area, with a focus on or substantial exposure to PBPK modelling. You must have demonstrated experience in developing and applying PBPK models, using platforms such as Simcyp, PK-Sim, GastroPlus, or equivalent. It is essential that you have excellent communication skills, including the ability to write publications, present research proposals and results, and represent the research group at meetings.
Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.
In addition to the salary, the successful candidate may receive the appropriate overseas allowances applicable to the location and appointment, in line with University policy.
This position is offered full time on a fixed term contract for 12 months and is funded by DNDI.
Only applications received before 12 midday on 30 July 2026 will be considered. Please quote 187232 on all correspondence.