Research Associate
entelo bio
Date: 10 hours ago
City: Oxford, England
Contract type: Full time
Location: Oxford, UK (BioEscalator)
Employment Type: Full-time
Salary: Competitive
About Entelo Bio
Entelo Bio is redefining the boundaries of precision medicine. Harnessing advanced machine learning and proprietary single-cell sequencing technologies, we're pioneering a new era of therapeutic discovery beyond traditional gene expression analysis. Our revolutionary platform is transforming target discovery to develop medicines for millions of patients with unmet clinical needs. We are venture-financed by global investors and located in Oxford's prestigious BioEscalator facility, supporting high-performing startups in the life sciences.
The Opportunity
We are seeking a Research Technician to join our laboratory team and play a critical role in our human tissue research program. This position offers the opportunity to apply a wide range of molecular biology techniques, including high-quality nucleic acid extraction, RNAseq library preparation, and long-read sequencing, in support of our precision medicine research. Based in Oxford's BioEscalator facility, you'll work independently under the strategic guidance of our CTO, making direct contributions to our scientific discoveries.
Key Responsibilities
Compensation & Benefits
Please submit your CV along with a brief cover letter explaining your interest in the role and relevant experience. We are looking to fill this position as soon as possible.
Note: This is a junior-level position ideal for recent Master's or PhD graduates seeking to gain industry experience in a dynamic, venture-backed biotech environment.
Employment Type: Full-time
Salary: Competitive
About Entelo Bio
Entelo Bio is redefining the boundaries of precision medicine. Harnessing advanced machine learning and proprietary single-cell sequencing technologies, we're pioneering a new era of therapeutic discovery beyond traditional gene expression analysis. Our revolutionary platform is transforming target discovery to develop medicines for millions of patients with unmet clinical needs. We are venture-financed by global investors and located in Oxford's prestigious BioEscalator facility, supporting high-performing startups in the life sciences.
The Opportunity
We are seeking a Research Technician to join our laboratory team and play a critical role in our human tissue research program. This position offers the opportunity to apply a wide range of molecular biology techniques, including high-quality nucleic acid extraction, RNAseq library preparation, and long-read sequencing, in support of our precision medicine research. Based in Oxford's BioEscalator facility, you'll work independently under the strategic guidance of our CTO, making direct contributions to our scientific discoveries.
Key Responsibilities
- Nucleic Acid Processing: Perform high-quality nucleic acid extraction and RNAseq library preparation from human tissue samples
- Sequencing Execution: Conduct sequencing runs using the Oxford Nanopore or PacBio platform
- Tissue Culture: Maintain cell lines and perform primary cell culture work from human tissue samples
- Sample Processing & Biobanking: Process, catalogue, and store biological samples according to strict quality standards
- Assay Development: Implement standardised protocols and assist in assay optimisation
- Tissue Analysis: Perform tissue sectioning and immunohistochemistry when required
- HTA Compliance: Maintain compliance with Human Tissue Authority (HTA) regulations and documentation requirements
- Data Management: Ensure accurate record-keeping and sample tracking (e.g. ELN and LIMS)
- Quality Control: Monitor and maintain high standards across all laboratory procedures
- General Lab Expertise: Ability to perform standard wet-lab procedures with high reproducibility, maintain accurate lab notebooks, and work safely in a regulated environment
- Education: Bachelor's/Master's/PhD in Molecular Biology, Biochemistry, Cell Biology, or related field
- Experience: 1-2+ years of hands-on laboratory experience (strong academic experience sufficient but excluding undergraduate labs)
- Molecular Biology Skills: Proven expertise in a broad range of molecular biology techniques, with an emphasis on nucleic acid extraction and RNA-seq library preparation
- Tissue Handling: Experience working with human tissues and biological samples
- Cell Culture: Solid tissue culture skills and sterile technique
- Independence: Ability to work autonomously while collaborating effectively with the team
- Attention to Detail: Meticulous approach to experimental protocols and documentation
- Long-read Experience: Hands-on experience with ONT or PacBio sequencing platforms
- Histological Techniques: Experience with tissue sectioning and immunohistochemistry
- HTA Knowledge: Familiarity with Human Tissue Authority regulations or willingness to train
- Assay Development: Experience in setting up and optimising new laboratory assays
- Biobanking: Knowledge of sample storage and biobanking best practices
Compensation & Benefits
- Competitive salary
- Employee Share Option Plan (ESOP)
- Comprehensive medical insurance
- Pension contributions
- Gym subsidy
- Cycle to work scheme
- Conference and professional development budget
- Flexible working arrangements
- Opportunity to work with cutting-edge genomics technologies
- Training in HTA compliance and regulatory frameworks
- Direct impact on precision medicine research
- Collaborative, interdisciplinary team environment
- Oxford BioEscalator - a prestigious facility supporting high-performing life science startups
- Scientific Excellence: Transparency and rigour drive us. Every result—positive or negative—is a step forward.
- Extreme Ownership: We take responsibility, solve problems, and get things done
- Impact-Driven: We are motivated by the difference we can make for patients and science
- Kindness: Flexibility, respect, and personal agency define our approach to teamwork.
- Ambition: We aim high, investing in ourselves and each other to achieve extraordinary goals
Please submit your CV along with a brief cover letter explaining your interest in the role and relevant experience. We are looking to fill this position as soon as possible.
Note: This is a junior-level position ideal for recent Master's or PhD graduates seeking to gain industry experience in a dynamic, venture-backed biotech environment.
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